Endocrine Abstracts

Kisspeptin is found in the ovary of different species including human and rat. We have recently described, through in vitro studies, that kisspeptin is under the control of sympathetic innervation of the ovary. Considering that ovarian activity of sympathetic nerves increases with ageing, it is possible that the ovarian kisspeptin also increases during this period. As a role of kisspeptin in folliculogenesis has been postulated, this increase in kisspeptin could parti...

Reports in the literature have demonstrated an increased number of nerve fibers and the presence of a follicle development similar to polycystic ovary during perimenopausal ovary in women. Since differentiation, proliferation and growth of nerves depends of nerve growth factor (NGF), changes in the content of nerves fiber could be preceded by increases in NGF and p75 neurotrophin receptor (p75NTR). Our purpose was to evaluate the changes in noradrenaline (NA) at the celiac gan...